FCGR2A wt Allele

Preferred Label : FCGR2A wt Allele;

NCIt synonyms : CD32; Fc Fragment of IgG, Low Affinity IIA, Receptor (CD32) wt Allele; IGFR2; FCG2; CD32A; FCGR2; RP11-5K23.6; Fc Fragment of IgG, Low Affinity IIa, Receptor for Gene; Fc Fragment of IgG, Low Affinity IIa, Receptor for (CD32) Gene; CDw32; FcGR; FCGR2A1;

NCIt definition : Human FCGR2A wild-type allele is located within 1q23 and is approximately 14 kb in length. This allele, which encodes low affinity immunoglobulin gamma Fc region receptor II-a protein, plays a role in receptor signal transduction and may be involved in collagen-mediated platelet activation.;

GenBank Accession Number : NM_021642;

Details

Origin ID

C51390;

UMLS CUI

C1705974;

OMIM relation
- Fc gamma receptor iia [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Lupus Glomerulonephritis [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 1: 158288316-158302322 [NCIt concept]
gene_in_chromosomal_location
- 1q23 [NCIt concept]
gene_is_element_in_pathway
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- PTPN1 Signaling Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
gene_plays_role_in_process
- Calcium Signaling [NCIt concept]
- Immune Response Process [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Ligand Binding [NCIt concept]
- Phagocytosis [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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