LIFR wt Allele

Preferred Label : LIFR wt Allele;

NCIt synonyms : SWS; Leukemia Inhibitory Factor Receptor Gene; SJS2; LIF-R; Leukemia Inhibitory Factor Receptor Alpha wt Allele; STWS; CD118;

NCIt definition : Human LIFR wild-type allele is located within 5p13-p12 and is approximately 116 kb in length. This allele, which encodes leukemia inhibitory factor receptor protein, is involved in the regulation of differentiation, survival and proliferation for a variety of cell types in both the adult and developing embryo.;

GenBank Accession Number : NM_002310;

Details

Origin ID

C51374;

UMLS CUI

C1708620;

Automatic exact mappings (from CISMeF team)
- CD118 cells [LOINC component]
- LIF receptor subunit alpha [ORDO Gene]
- Leukemia inhibitory factor receptor [OMIM gene]
- Sturge-Weber syndrome [ORDO Disease]
- Sturge-Weber syndrome [DO Concept]
- Sturge-weber syndrome [OMIM Phenotype]
- Stuve-wiedemann syndrome 1 [OMIM Phenotype]
- Stüve-Wiedemann syndrome [ORDO Disease]
- leukemia inhibitory factor receptor alpha subunit [MeSH Descriptor]
- patatin like phospholipase domain containing 6 [ORDO Gene]
- receptors, osm-lif [MeSH Descriptor]
OMIM relation
- Leukemia inhibitory factor receptor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 5: 38631253-38515662 [NCIt concept]
gene_in_chromosomal_location
- 5p13-p12 [NCIt concept]
gene_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Hematopoietic Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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