IFNAR2 wt Allele

Preferred Label : IFNAR2 wt Allele;

NCIt synonyms : Interferon (Alpha, Beta and Omega) Receptor 2 wt Allele; IFNARB;

NCIt definition : Human IFNAR2 wild-type allele is located in the vicinity of 21q22.11 and is approximately 35 kb in length. This allele, which encodes interferon alpha/beta receptor 2 protein, plays a role in tyrosine-kinase signal transduction and the mediation of innate immune responses to viral infection.;

GenBank Accession Number : NM_000874;

Details

Origin ID

C51353;

UMLS CUI

C1708408;

OMIM relation
- Interferon-alpha, -beta, and -omega receptor 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 21: 33524101-33558697 [NCIt concept]
gene_in_chromosomal_location
- 21q22.1 [NCIt concept]
gene_is_element_in_pathway
- Bone Remodeling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- IFN Alpha Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Antiviral Response [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interferon Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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