TBK1 wt Allele

Preferred Label : TBK1 wt Allele;

NCIt synonyms : T2K; NF-Kb-Activating Kinase Gene; FLJ11330; TANK Binding Kinase 1 wt Allele; NAK; FTDALS4; TANK-Binding Kinase 1 Gene;

NCIt definition : Human TBK1 wild-type allele is located in the vicinity of 12q14.1 and is approximately 50 kb in length. This allele, which encodes serine/threonine-protein kinase TBK1 protein, is involved in the innate immune response and mediation of transcription factor NF-kappa-B activation in response to certain growth factors.;

GenBank Accession Number : NM_013254;

Details

Origin ID

C51328;

UMLS CUI

C1705042;

OMIM relation
- Tank-binding kinase 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 12q14.1 [NCIt concept]
gene_is_element_in_pathway
- Cytosolic DNA-Sensing Pathway [NCIt concept]
- NOD-Like Receptor Signaling Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
- Toll-Like Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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