" /> MAP3K8 wt Allele - CISMeF





Preferred Label : MAP3K8 wt Allele;

NCIt synonyms : c-COT; Cancer Osaka Thyroid Gene; COT; Augmented in Rheumatoid Arthritis 2 Gene; Mitogen-Activated Protein Kinase Kinase Kinase 8 wt Allele; COT (Cancer Osaka Thyroid) Oncogene; COT Gene; Proto-Oncogene Serine/Threoine Protein Kinase Gene; EST; Cancer Osaka Thyroid Oncogene; TPL-2; ESTF; Tumor Progression Locus 2 Gene; TPL2; MEKK8; Ewing Sarcoma Transformant Gene; Tumor Progression Locus-2 Gene; AURA2;

NCIt definition : Human MAP3K8 wild-type allele is located in the vicinity of 10p11.23 and is approximately 28 kb in length. This allele, which encodes mitogen-activated protein kinase kinase kinase 8 protein, is pleiotropic due to its role in several signaling pathways that are involved in processes such as cell cycle regulation and T-cell activation.;

NCIt note : The MAP3K8 gene encodes two isoforms of mitogen-activated protein kinase kinase kinase 8 protein via alternative initiation.;

GenBank Accession Number : NM_005204;

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16/05/2024


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