GRK6 wt Allele

Preferred Label : GRK6 wt Allele;

NCIt synonyms : GPRK6; G Protein-Coupled Receptor Kinase 6 wt Allele; GPRK6 wt Allele;

NCIt definition : Human GRK6 wild-type allele is located within 5q35 and is approximately 16 kb in length. This allele, which encodes G protein-coupled receptor kinase 6 protein, plays a role in the deactivation of G protein-coupled receptors.;

NCIt note : The GRK6 gene is putatively involved in the desensitization of dopamine receptors D2 and D3. This gene encodes two isoforms of the G protein-coupled receptor kinase 6 protein (GPRK6 isoforms alpha and beta).;

GenBank Accession Number : NM_002082;

Details

Origin ID

C51204;

UMLS CUI

C1705400;

OMIM relation
- G protein-coupled receptor kinase 6 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 5: 176786389-176802456 [NCIt concept]
gene_in_chromosomal_location
- 5q35 [NCIt concept]
gene_is_element_in_pathway
- CXCR4-Mediated Signaling Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
gene_plays_role_in_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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