TEC wt Allele - CISMeF

Preferred Label : TEC wt Allele;

NCIt synonyms : Tec Protein Tyrosine Kinase wt Allele; PSCTK4;

NCIt definition : Human TEC wild-type allele is located within 4p12 and is approximately 134 kb in length. This allele, which encodes tyrosine-protein kinase Tec protein, plays a role in both T-cell activation and T-cell signaling.;

NCIt note : The TEC gene may be associated with myelodysplastic syndrome, as expression of this gene is elevated in a small population of patients with this disorder.;

GenBank Accession Number : NM_003215;

Détails

Origin ID

C51158;

UMLS CUI

C1710286;

OMIM relation
- Tec protein tyrosine kinase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- Myelodysplastic Syndrome [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 4p12 [NCIt concept]
gene_is_element_in_pathway
- Erythropoietin Signaling Pathway [NCIt concept]
- Mast/Stem Cell Growth Factor Receptor Signaling Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Immunoregulation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- T-Cell Activation [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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