DLG1 wt Allele

Preferred Label : DLG1 wt Allele;

NCIt synonyms : Discs, Large Homolog 1 (Drosophila) wt Allele; HDLG; SAP97;

NCIt definition : Human DLG1 wild-type allele is located within 3q29 and is approximately 254 kb in length. This allele, which encodes disks large homolog 1 protein, is involved in both organization of the actin cytoskeleton and coupling of this structure to the cell membrane.;

NCIt note : In polarized cells, the DLG1 gene product plays a role in the recruitment of channels, receptors and signaling molecules to discrete plasma membrane domains. Although Dlg1 is a putative tumor suppressor protein, it has been shown to be involved in virus-mediated cellular transformation.;

GenBank Accession Number : NM_004087;

Details

Origin ID

C51056;

UMLS CUI

C1705671;

OMIM relation
- Discs large maguk scaffold protein 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 3: 198513757-198259733 [NCIt concept]
gene_in_chromosomal_location
- 3q29 [NCIt concept]
gene_is_element_in_pathway
- Synaptic Junction Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation [NCIt concept]
- Regulation of Cell Shape [NCIt concept]

Keyword's position in hierarchy(ies) :

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