TYMS wt Allele

Preferred Label : TYMS wt Allele;

NCIt synonyms : TS; Thymidylate Synthase wt Allele; TMS;

NCIt definition : Human TYMS wild-type allele is located in the vicinity of 18p11.32 and is approximately 16 kb in length. This allele, which encodes thymidylate synthase protein, is involved in maintenance of the thymidine-5'-monophosphate (dTMP) pool necessary for DNA replication and repair. Certain allelic variants of the TYMS gene confer resistance to chemotherapy.;

GenBank Accession Number : NM_001071;

Details

Origin ID

C51047;

UMLS CUI

C1705746;

Automatic exact mappings (from CISMeF team)
- Body temperature [LOINC component]
- Gilles de la tourette syndrome [OMIM Phenotype]
- Growth control, y-chromosome influenced [OMIM Phenotype]
- Lower case Roman letter t (qualifier value) [SNOMED CT concept]
- Pyd and card domain-containing protein [OMIM gene]
- T category (observable entity) [SNOMED CT concept]
- Temperature [LOINC component]
- Temperature [LOINC Property]
- Tetanus toxoid [UNVA Valence]
- Thymidylate synthetase [OMIM gene]
- Timothy syndrome [OMIM Phenotype]
- Tropical sprue [ICD-11 Sub-sub category]
- Tuberous sclerosis 1 [OMIM Phenotype]
- Tympanosclerosis [ICD-11 Category]
- Upper case Roman letter T (qualifier value) [SNOMED CT concept]
- Virus-associated trichodysplasia spinulosa [ORDO Disease]
- calcium voltage-gated channel subunit alpha1 C [ORDO Gene]
- chemical shift [IUPAC Quantity]
- disease transmission, infectious [MeSH Descriptor]
- temperature [MeSH Descriptor]
- thromboxane A synthase 1 [ORDO Gene]
- thymidylate synthetase [ORDO Gene]
- transcranial magnetic stimulation [MeSH Descriptor]
False automatic mappings
- Tourette syndrome [ORDO Disease]
OMIM relation
- Thymidylate synthetase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 18p11.32 [NCIt concept]
gene_is_element_in_pathway
- Folate Biosynthesis Pathway [NCIt concept]
- One Carbon Pool by Folate Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Repair [NCIt concept]
- DNA Replication [NCIt concept]
- Methylation [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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