Preferred Label : Gilles de la tourette syndrome;
Symbol : GTS;
CISMeF acronym : GTS; TS;
Type : Phenotype, molecular basis known;
Alternative titles and symbols : Tourette syndrome; Tourette disorder; TS;
Included titles and symbols : Chronic motor tics;
Description : Tourette syndrome is a neurobehavioral disorder manifest particularly by motor and
vocal tics and associated with behavioral abnormalities. Tics are sudden, brief, intermittent,
involuntary or semi-voluntary movements (motor tics) or sounds (phonic or vocal tics).
They typically consist of simple, coordinated, repetitive movements, gestures, or
utterances that mimic fragments of normal behavior. Motor tics may range from simple
blinking, nose twitching, and head jerking to more complex throwing, hitting, or making
rude gestures. Phonic tics include sniffling, throat clearing, blowing, coughing,
echolalia, or coprolalia. Males are affected about 3 times more often than females,
and onset usually occurs between 3 and 8 years of age. By age 18 years, more than
half of affected individuals are free of tics, but they may persist into adulthood
(review by Jankovic, 2001).;
Inheritance : Autosomal dominant;
Prefixed ID : #137580;
Origin ID : 137580;
UMLS CUI : C0040517;
Automatic exact mappings (from CISMeF team)
Currated CISMeF NLP mapping
DO Cross reference
False automatic mappings
Genes related to phenotype
HPO term(s)
ORDO concept(s)
Semantic type(s)
UMLS correspondences (same concept)