FBXW7 wt Allele

Preferred Label : FBXW7 wt Allele;

NCIt synonyms : SEL10; AGO; SEL-10; F-Box and WD Repeat Domain Containing 7 wt Allele; hAgo; FBX30; FLJ11071; CDC4; FBW7; Archipelago Homolog; F-Box And WD Repeat Domain Containing 7, E3 Ubiquitin Protein Ligase Gene; F-box and WD-40 Domain Protein 7 (Archipelago Homolog, Drosophila) Gene; FBW6; hCdc4; FBXW6; Archipelago Homolog, Drosophila Gene; Archipelago Homolog, Drosophila, Homolog of Gene; SEL10, C. elegans, Homolog of Gene; CDC4, S. cerevisiae, Homolog of Gene; FBXO30;

NCIt definition : Human FBXW7 wild-type allele is located in the vicinity of 4q31.3 and is approximately 91 kb in length. This allele, which encodes F-box/WD-repeat protein 7, is involved in ubiquitin-dependent protein degradation and has been implicated in the maintenance of genomic integrity.;

GenBank Accession Number : NM_033632;

Details

Origin ID

C50390;

UMLS CUI

C1704938;

OMIM relation
- F-box and wd40 domain protein 7 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 4: 153690635-153601100 [NCIt concept]
gene_in_chromosomal_location
- 4q31.23 [NCIt concept]
gene_is_element_in_pathway
- Cyclin E Degradation Pathway [NCIt concept]
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
gene_plays_role_in_process
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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