Preferred Label : CXCL13 wt Allele;
NCIt synonyms : SCYB13; BCA1; BLR1L; ANGIE2; BLC; BCA-1; Chemokine (C-X-C Motif) Ligand 13 wt Allele; Small Inducible Cytokine Subfamily B, Member 13 Gene; Chemokine (C-X-C Motif) Ligand 13 (B-Cell Chemoattractant) Gene; B-Cell-Homing Chemokine (Ligand For Burkitt's Lymphoma Receptor-1) Gene; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 13 Gene; Chemokine, CXC Motif, Ligand 13 Gene; ANGIE; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 13 (B-Cell Chemoattractant)
Gene;
NCIt definition : Human CXCL13 wild-type allele is located within 4q21 and is approximately 100 kb in
length. This allele, which encodes C-X-C motif chemokine 13 protein, is involved in
B lymphocyte migration and chemotaxis.;
NCIt note : CCL13 is induced by IL-1 and TNF-alpha and widely expressed. The cytokine encoded
by this gene displays chemotactic activity for monocytes, lymphocytes, basophils and
eosinophils, but not neutrophils. This chemokine plays a role in accumulation of leukocytes
during inflammation. It may also be involved in the recruitment of monocytes into
the arterial wall during artherosclerosis. This gene stimulates eosinophil to signal
through CCR2B and CCR3 receptors and is involved in immunoregulatory and inflammatory
processes.;
GenBank Accession Number : NM_006419;
Origin ID : C49761;
UMLS CUI : C1704465;
OMIM relation
- Semantic type(s)
- concept_is_in_subset
- gene_found_in_organism
- gene_has_physical_location
- gene_in_chromosomal_location
- gene_is_element_in_pathway
- gene_plays_role_in_process
