PLAT wt Allele

Preferred Label : PLAT wt Allele;

NCIt synonyms : Plasminogen Activator, Tissue wt Allele; TPA; Plasminogen Activator, Tissue Type Gene;

NCIt definition : Human PLAT wild-type allele is located within 8p12 and is approximately 32 kb in length. This allele, which encodes tissue-type plasminogen activator protein, is involved in the regulation of plasmin-mediated proteolysis via the conversion of the proenzyme plasminogen to plasmin.;

GenBank Accession Number : NM_000930;

Details

Origin ID

C49737;

UMLS CUI

C1706149;

Automatic exact mappings (from CISMeF team)
- Plasminogen activator tissue type [LOINC component]
- Plasminogen activator, tissue [OMIM gene]
- Product containing alteplase (medicinal product) [SNOMED CT concept]
- Tissue plasminogen activator (substance) [SNOMED CT concept]
- obsolete plasminogen activator activity [GO term]
- tPA stop [MeSH concept]
- tPA stop [MeSH Supplementary Concept]
- taurine-pyruvate aminotransferase activity [GO term]
OMIM relation
- Plasminogen activator, tissue [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 8p12 [NCIt concept]
gene_is_element_in_pathway
- Acute Myocardial Infarction Pathway [NCIt concept]
- AlphaM/Beta2 Integrin Signaling Pathway [NCIt concept]
- Complement and Coagulation Cascade [NCIt concept]
- Fibrinolysis Pathway [NCIt concept]
- Keratinocyte Differentiation Pathway [NCIt concept]
- Platelet Amyloid Precursor Protein Pathway [NCIt concept]
gene_plays_role_in_process
- Cellular Migration Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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