CCNA2 wt Allele

Preferred Label : CCNA2 wt Allele;

NCIt synonyms : CGA2; CCN1; Cyclin A2 wt Allele; CCNA;

NCIt definition : Human CCNA2 wild-type allele is located within 4q25-q31 and is approximately 6 kb in length. This allele, which encodes cyclin-A2 protein, plays a role in cell cycle G1/S and G2/M transitions.;

NCIt note : CCNA2 is repressed during G1 and activated at S-phase. This gene, is transcribed into 1.8- and 2.7-kb mRNAs in all tissues tested (highest in testis). Cell cycle gene regulation is mediated by sequences surrounding the transcription start site.;

GenBank Accession Number : NM_001237;

Details

Origin ID

C49515;

UMLS CUI

C1705080;

OMIM relation
- Cyclin a2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- Hepatocellular Carcinoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 4: 123102497-123096130 [NCIt concept]
gene_in_chromosomal_location
- 4q25-q31 [NCIt concept]
gene_is_element_in_pathway
- Cell Cycle Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Process [NCIt concept]
- Cell Cycle Regulation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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