DUSP1 wt Allele

Preferred Label : DUSP1 wt Allele;

NCIt synonyms : Dual Specificity Phosphatase 1 wt Allele; HVH1; MKP-1; PTPN10; Serine/Threonine Specific Protein Phosphatase Gene; CL100;

NCIt definition : Human DUSP1 wild-type allele is located within 5q34 and is approximately 3 kb in length. This allele, which encodes dual specificity protein phosphatase 1 protein, is involved in the dephosphorylation of both protein tyrosine phosphates and phosphoproteins. Decreased expression of the DUSP1 gene is associated with ovarian cancer.;

GenBank Accession Number : NM_004417;

Details

Origin ID

C49417;

UMLS CUI

C1705047;

OMIM relation
- Dual-specificity phosphatase 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 5: 172130809-172127707 [NCIt concept]
gene_in_chromosomal_location
- 5q34 [NCIt concept]
gene_is_element_in_pathway
- ATF-2 Transcription Factor Signaling Pathway [NCIt concept]
- CD40L Signaling Pathway [NCIt concept]
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- MAP Kinase Regulation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- NFKB Activation Pathway [NCIt concept]
- PPAR-alpha Gene Regulation Pathway [NCIt concept]
- Regulation of p38-alpha and p38-beta Pathway [NCIt concept]
- TNFR2 Signaling Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_plays_role_in_process
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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