SKIC2 wt Allele

Preferred Label : SKIC2 wt Allele;

NCIt synonyms : Superkiller Viralicidic Activity 2-Like Gene; HLP; DDX13; SKI2W; SKIV2; SKI2; THES2; 170A; Ski2 Like RNA Helicase Gene; Superkiller Viralicidic Activity 2 (S. cerevisiae Homolog)-Like Gene; SKI2 Homolog, Superkiller Viralicidic Activity 2-Like Gene; SKIV2L1; Superkiller Viralicidic Activity 2-Like (S. cerevisiae) Gene; W; Helicase SKI2W Gene; SKIV2L; SKIV2L wt Allele; SKI2 Subunit of Superkiller Complex wt Allele; SKI2 Subunit of Superkiller Complex Protein Gene;

NCIt definition : Human SKIC2 wild-type allele is located in the vicinity of 6p21.33 and is approximately 11 kb in length. This allele, which encodes superkiller complex protein 2, plays a role in exosomal degradation of RNA in the mRNA decay and quality-control pathways. Mutation of the gene is associated with trichohepatoenteric syndrome 2.;

GenBank Accession Number : NM_006929;

Details

Origin ID

C49412;

UMLS CUI

C1705260;

OMIM relation
- Ski2 subunit of superkiller complex [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 6p21.33 [NCIt concept]
gene_is_element_in_pathway
- RNA Degradation Pathway [NCIt concept]
gene_plays_role_in_process
- ATP Hydrolysis [NCIt concept]
- Hydrolysis [NCIt concept]
- Nonsense-Mediated Decay [NCIt concept]
- RNA Degradation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients