EF-1 Peptide - CISMeF

Preferred Label : EF-1 Peptide;

NCIt synonyms : EWS/FLI 1 Type 1;

NCIt related terms : EWS/FLI 1 (type 1);

NCIt definition : A synthetic peptide derived from the protein ESW/FLI1 type 1 with potential use in cancer immunotherapy. EWS/FLI1 is a fusion protein frequently found in patients with Ewing's sarcoma or primitive neuroectodermal tumors (PNET). Vaccination with EF-1 peptide may stimulate the host immune response to elicit a cytotoxic T-cell response against tumor cells that express this EWS/FL1 type 1 fusion protein.;

NSC code : 686674;

Codes from synonyms : NSC0686674;

Details

Origin ID

C49063;

UMLS CUI

C1707842;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
has_target
- Serine/Threonine-Protein Kinase mTOR [NCIt concept]

Keyword's position in hierarchy(ies) :

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