" /> Azathioprine Sodium - CISMeF





Preferred Label : Azathioprine Sodium;

NCIt related terms : Imuran; Imurel;

NCIt definition : The sodium salt form of azathioprine, a pro-drug of purine analogue with immunosuppressive activity. Azathioprine is converted in vivo to its active metabolite 6-mercaptopurine (6-MP), which substitutes for the normal nucleoside and mistakenly gets incorporated into DNA sequences. This leads to inhibition of DNA, RNA, and protein synthesis. As a result, cell proliferation may be inhibited, particularly in lymphocytes and leukocytes.;

Alternative definition : NCI-GLOSS: A drug used to keep a patient from rejecting a transplanted kidney. It is also used in the treatment of rheumatoid arthritis that does not get better with other types of treatment. Azathioprine sodium blocks the growth of white blood cells and the synthesis of DNA, RNA, and protein. It is a type of immunosuppressant.;

UNII : AM94R510MS;

InChIKey : WISNYKIQFMKSDQ-UHFFFAOYSA-N;

CAS number : 55774-33-9;

Drug name : Imurel; Imuran;

Chemical formula : C9H6N7O2S.Na;

Codes from synonyms : NSC0039084; CDR0000648945;

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04/07/2025


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