" /> Amrubicin Hydrochloride - CISMeF





Preferred Label : Amrubicin Hydrochloride;

NCIt synonyms : ( )-(7S,9S)-9-Acetyl-9-amino-7-((2-deoxy-beta-D-erythro-pentopyranosyl)oxy)- 6,11-dihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride; Amrubicin HCl;

NCIt definition : The hydrochloride salt of a third-generation synthetic 9-amino-anthracycline with antineoplastic activity. Amrubicin intercalates into DNA and inhibits the activity of topoisomerase II, resulting in inhibition of DNA replication, and RNA and protein synthesis, followed by cell growth inhibition and cell death. This agent has demonstrated a higher level of anti-tumor activity than conventional anthracycline drugs without exhibiting any indication of the cumulative cardiac toxicity common to this class of compounds.;

UNII : EUL6MP8FZW;

InChIKey : BHMLHEQFWVQAJS-IITOGVPQSA-N;

CAS number : 110311-30-3; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 110311-30-3 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Calsed;

Molecule name : SM-5887; SMP-5887;

Chemical formula : C25H25NO9.ClH;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
12/05/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.