Recombinant Erythropoietin

Preferred Label : Recombinant Erythropoietin;

NCIt synonyms : Erythrocyte Colony Stimulating Factor; Erythropoietin; Hematopoietin; Recombinant EPO;

NCIt related terms : EPOETIN;

NCIt definition : A recombinant therapeutic agent which is chemically identical to or similar to the endogenous glycoprotein erythropoietin (Epo). Epo promotes the differentiation and maturation of hematopoietic progenitors into erythrocytes; is a mitogen and a chemoattractant for endothelial cells; stimulates activated and differentiated B-cells and enhances B-cell immunoglobulin production and proliferation; and is hypoxia-inducible. (NCI04);

UNII : 64FS3BFH5W;

CAS number : 11096-26-7;

NSC code : 628281;

Details

Origin ID

C477;

UMLS CUI

C0376541;

Automatic exact mappings (from CISMeF team)
- Erythropoietin [OMIM gene]
- Erythropoietin given [LOINC component]
- Product containing erythropoietin (medicinal product) [Inactive SNOMED CT concept]
- erythropoietin [HGNC gene]
- erythropoietin receptor binding [GO term]
- hematopoietic cell growth factors [MeSH Descriptor]
- hematopoietic cell growth factors [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- Erythropoietin [SMS substance]
- Erythropoietin (substance) [SNOMED CT concept]
- erythropoietin [ATC Code]
chemical_or_drug_affects_gene_product
- Erythropoietin Receptor [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Receptor Activation Process [NCIt concept]
chemical_or_drug_has_physiologic_effect
- B-Cell Activation [NCIt concept]
- Hematopoiesis Induction [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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