Proparacaine Hydrochloride

Preferred Label : Proparacaine Hydrochloride;

NCIt synonyms : Keracaine; Alcaine; Ophthetic; 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate Monohydrochloride; Benzoic Acid, 3-Amino-4-propoxy-, 2-(diethylamino)ethyl Ester, Hydrochloride; Proxymetacaine Hydrochloride;

NCIt definition : The hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. Proparacaine hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels, thereby inhibiting sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, and resulting in a loss of sensation.;

UNII : U96OL57GOY;

InChIKey : BFUUJUGQJUTPAF-UHFFFAOYSA-N;

CAS number : 5875-06-9;

Chemical formula : C16H26N2O3.HCl;

Details

Origin ID

C47693;

UMLS CUI

C0740235;

Automatic exact mappings (from CISMeF team)
- Ophthetic [ICHI extension code]
- Proxymetacaine hydrochloride product (product) [Inactive SNOMED CT concept]
- endophthalmitis [MeSH Descriptor]
- kainair [MeSH concept]
- proxymetacaine [MeSH Supplementary Concept]
- proxymetacaine hydrochloride [MeSH concept]
- proxymetacaine hydrochloride [Substance BNPC]
Currated CISMeF NLP mapping
- Ophthetic [ICD-11 Extension code]
- Proxymetacaine hydrochloride (substance) [SNOMED CT concept]
- alcaine [MeSH concept]
- ophthetic [MeSH concept]
- proparacaine hydrochloride [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Ophthetic [ICD-11 Extension code]
- Proxymetacaine hydrochloride (substance) [SNOMED CT concept]
- Proxymetacaine hydrochloride product (product) [Inactive SNOMED CT concept]
- proparacaine hydrochloride [SNOMED Notion]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Proparacaine [NCIt concept]
is_salt_form_of
- Proparacaine [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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