Proparacaine - CISMeF

Preferred Label : Proparacaine;

NCIt synonyms : 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate; 3-Amino-4-propoxybenzoic acid 2-(diethylamino)ethyl Ester; Proxymetacaine;

NCIt definition : A benzoic acid derivative anesthetic agent, with local anesthetic activity. Upon administration, proparacaine stabilizes the neuronal membrane by binding to and inhibiting voltage-gated sodium channels. This inhibits the sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, increases the threshold for electrical stimulation and results in a loss of sensation.;

UNII : B4OB0JHI1X;

InChIKey : KCLANYCVBBTKTO-UHFFFAOYSA-N;

CAS number : 499-67-2;

Chemical formula : C16H26N2O3;

Details

Origin ID

C61910;

UMLS CUI

C0072510;

Automatic exact mappings (from CISMeF team)
- Product containing proxymetacaine (medicinal product) [SNOMED CT concept]
- Proparacaine [ICHI extension code]
- Proxymetacaine [ICD-11 Extension code]
- Proxymetacaine [ICHI extension code]
- Proxymetacaine (substance) [SNOMED CT concept]
- proxymetacaine [ATC Code]
- proxymetacaine [MeSH Supplementary Concept]
- proxymetacaine [MeSH concept]
- proxymetacaine [Substance BNPC]
Currated CISMeF NLP mapping
- Proparacaine [ICD-11 Extension code]
- proparacaine [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing proxymetacaine (medicinal product) [SNOMED CT concept]
- Proparacaine [ICD-11 Extension code]
- Proxymetacaine [ICD-11 Extension code]
- Proxymetacaine (substance) [SNOMED CT concept]
- proparacaine [SNOMED Notion]
- proxymetacaine [ATC Code]
- proxymetacaine [Substance BNPC]
- proxymetacaine [MeSH concept]
- proxymetacaine [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_salt_form
- Proparacaine Hydrochloride [NCIt concept]
is_free_acid_or_base_form_of
- Proparacaine Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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