Meclofenamate Sodium

Preferred Label : Meclofenamate Sodium;

NCIt synonyms : Meclonax; Benzoic Acid, 2-((2,6-dichloro-3-methylphenyl)amino)-, Monosodium Salt; Sodium 2-((2,6-dichloro-3-methylphenyl)amino)benzoate;

NCIt related terms : Meclofenamate Sodium Salt;

NCIt definition : The sodium salt form of meclofenamate, an anthranilic acid and non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesic activities. Meclofenamate sodium inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of meclofenamate sodium. Meclofenamate sodium also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.;

UNII : 94NJ818U2W;

InChIKey : QHJLLDJTVQAFAN-UHFFFAOYSA-M;

CAS number : 6385-02-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 6385-02-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Meclomen;

Chemical formula : C14H10Cl2NO2.Na.H2O;

Codes from synonyms : 05222;

Details

Origin ID

C47597;

UMLS CUI

C0025041;

Currated CISMeF NLP mapping
- Meclofenamate Sodium [MeSH concept]
- Meclofenamate sodium (substance) [SNOMED CT concept]
- meclofenamate sodium [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Meclofenamate Sodium Anhydrous [MeSH concept]
- Meclofenamate sodium (substance) [SNOMED CT concept]
- Meclofenamate sodium product (product) [Inactive SNOMED CT concept]
- meclofenamate sodium [SNOMED Notion]
Validated automatic mappings to BTNT
- Meclofenamate Sodium Anhydrous [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Meclofenamic Acid [NCIt concept]
has_target
- Prostaglandin G/H Synthase 1 [NCIt concept]
- Prostaglandin G/H Synthase 2 [NCIt concept]
is_salt_form_of
- Meclofenamic Acid [NCIt concept]

Keyword's position in hierarchy(ies) :

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