Ketoprofen - CISMeF

Preferred Label : Ketoprofen;

NCIt synonyms : Capisten; Benzeneacetic Acid, 3-benzoyl-alpha-methyl-; Propionic Acid, 2-(3-benzoylphenyl)-;

NCIt definition : A propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.;

UNII : 90Y4QC304K;

InChIKey : DKYWVDODHFEZIM-UHFFFAOYSA-N;

CAS number : 22071-15-4;

Drug name : Orudis; Oruvail;

Chemical formula : C16H14O3;

ChEBI ID : CHEBI:6128;

Codes from synonyms : 804;

Details

Origin ID

C47578;

UMLS CUI

C0022635;

Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Ketoprofen [LOINC component]
- Ketoprofen (substance) [SNOMED CT concept]
- Product containing ketoprofen (medicinal product) [SNOMED CT concept]
- ketoprofen [ATC Code]
- ketoprofen [ATC Code]
- ketoprofen [Substance BNPC]
- ketoprofen [SNOMED Notion]
- ketoprofen [MeSH concept]
- ketoprofen [MeSH Descriptor]
Validated automatic mappings to BTNT
- ketoprofen [ATC Code]
- ketoprofen [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Prostaglandin G/H Synthase 1 [NCIt concept]
- Prostaglandin G/H Synthase 2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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