Desmopressin Acetate

Preferred Label : Desmopressin Acetate;

NCIt synonyms : 1-(3-Mercaptopropionic acid)-8-D-arginine Vasopression Monoacetate;

NCIt definition : An analogue of the hormone vasopressin with antidiuretic and antihemorrhagic properties. Desmopressin acetate has selective affinity for the V2 receptor and acts on the distal kidney tubule by increasing the cellular permeability thereby stimulating water reabsorption. This antidiuretic agent is used in the treatment of central diabetes insipidus. An unrelated action of desmopressin acetate is to increases circulating factor VIII and is used in patients with haemophilia and von Willebrand's disease.;

UNII : XB13HYU18U;

InChIKey : YNKFCNRZZPFMEX-XHPDKPNGSA-N;

CAS number : 62357-86-2;

Drug name : Octostim; Concentraid; DDAVP; Stimate;

Chemical formula : C46H64N14O12S2.C2H4O2.3H2O;

ChEBI ID : CHEBI:59728;

Details

Origin ID

C47475;

UMLS CUI

C0086135;

Automatic exact mappings (from CISMeF team)
- desmopressin [Substance BNPC]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to NTBT
- deamino arginine vasopressin [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_free_acid_or_base_form
- Desmopressin [NCIt concept]
is_salt_form_of
- Desmopressin [NCIt concept]

Keyword's position in hierarchy(ies) :

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