Desmopressin - CISMeF

Preferred Label : Desmopressin;

NCIt synonyms : 1-Deamino-8-D-arginine Vasopressin;

NCIt definition : A synthetic octapeptide, and an analogue of human hormone arginine vasopressin with antidiuretic and coagulant activities. Desmopressin binds to V2 receptors in renal collecting ducts which leads to exocytosis of von Willebrand factor (VWF) and tissue plasminogen activator (t-PA) from Weibel-Palade bodies, thereby increasing water resorption. This agent also increases nitric oxide (NO) production via activation of endothelial NO synthase, thereby induces afferent arteriolar vasodilation. Furthermore, desmopressin stimulates the release of factor VIII from endothelial cells mediated through V1a receptor, thereby promotes blood coagulation.;

UNII : ENR1LLB0FP;

InChIKey : NFLWUMRGJYTJIN-PNIOQBSNSA-N;

CAS number : 16679-58-6;

Chemical formula : C46H64N14O12S2;

ChEBI ID : CHEBI:4450;

Codes from synonyms : 155;

Details

Origin ID

C61701;

UMLS CUI

C0011701;

See also inter- (CISMeF)
- Product containing desmopressin (medicinal product) [SNOMED CT concept]
- desmopressin preparation [SNOMED Notion]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Desmopressin [ICD-11 Extension code]
- Desmopressin (substance) [SNOMED CT concept]
- Product containing desmopressin (medicinal product) [SNOMED CT concept]
- deamino arginine vasopressin [MeSH concept]
- deamino arginine vasopressin [MeSH Descriptor]
- desmopressin [ATC Code]
- desmopressin [Substance BNPC]
- desmopressin preparation [SNOMED Notion]
Validated automatic mappings to BTNT
- desmopressin [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
has_salt_form
- Desmopressin Acetate [NCIt concept]
is_free_acid_or_base_form_of
- Desmopressin Acetate [NCIt concept]

Keyword's position in hierarchy(ies) :

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