Preferred Label : Aprotinin;
NCIt synonyms : Aprotinin Bovine; Trypsin Inhibitor, Pancreatic Basic;
NCIt definition : A single chain polypeptide isolated from bovine lung with antifibrinolytic and anti-inflammatory
activities. As a broad-spectrum serine protease inhibitor, aprotinin bovine competitively
and reversibly inhibits the activity of a number of different esterases and proteases,
including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activator,
and tissue and leukocytic proteinases, resulting in attenuation of the systemic inflammatory
response (SIR), fibrinolysis, and thrombin generation. This agent also inhibits pro-inflammatory
cytokine release and maintains glycoprotein homeostasis.;
UNII : 04XPW8C0FL;
CAS number : 11005-72-4;
Drug name : TachoComb H; Trasylol;
Molecule name : RP-9921; Riker-52g; Bayer-A-128;
Chemical formula : C284H432N84O79S7;
Origin ID : C47402;
UMLS CUI : C0003641;
See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
