Preferred Label : Aprotinin;
NCIt synonyms : Aprotinin Bovine; Trypsin Inhibitor, Pancreatic Basic;
NCIt definition : A single chain polypeptide isolated from bovine lung with antifibrinolytic and anti-inflammatory
activities. As a broad-spectrum serine protease inhibitor, aprotinin bovine competitively
and reversibly inhibits the activity of a number of different esterases and proteases,
including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activator,
and tissue and leukocytic proteinases, resulting in attenuation of the systemic inflammatory
response (SIR), fibrinolysis, and thrombin generation. This agent also inhibits pro-inflammatory
cytokine release and maintains glycoprotein homeostasis.;
UNII : 04XPW8C0FL;
CAS number : 11005-72-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 11005-72-4
alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo
G-SRS /a ;
Drug name : TachoComb H; Trasylol;
Molecule name : RP-9921; Riker-52g; Bayer-A-128;
Chemical formula : C284H432N84O79S7;
Origin ID : C47402;
UMLS CUI : C0003641;
Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
