" /> CYP2D6*42 Allele - CISMeF





Preferred Label : CYP2D6*42 Allele;

NCIt synonyms : CYP2D6, g.3259insGT; Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*42 Allele; CYP2D6*42; CYP2D6 42 Allele;

NCIt definition : Human CYP2D6*42 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type allele, encodes cytochrome P450 2D6*42 protein. The CYP2D6*42 allele exhibits a two nucleotide insertion (g.3259insGT) that results in a frameshift during protein coding. This alteration abolishes the enzymatic activity of the cytochrome P450 2D6*42 protein.;

NCIt note : Ethnicity Association: African American;

GenBank Accession Number : NM_000106;

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20/05/2024


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