" /> CYP2D6*9 Allele - CISMeF





Preferred Label : CYP2D6*9 Allele;

NCIt synonyms : Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*9 Allele; CYP2D6, K281del; CYP2D6C; CYP2D6, g.2613delAGA; CYP2D6*9; CYP2D6 9 Allele;

NCIt definition : Human CYP2D6*9 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type allele, encodes cytochrome P450 2D6*9 protein. The CYP2D6*9 allele exhibits a deletion of three nucleotides (g.2613delAGA) at the 3' end of exon 5 that results in a K281 deletion during coding. This alteration in protein sequence decreases the enzymatic activity of the cytochrome P450 2D6*9 protein.;

NCIt note : Ethnicity Association: Asian; Caucasian; Middle Eastern;

GenBank Accession Number : NM_000106;

PubMed : 1844820; 8101460;

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20/05/2024


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