" /> CYP2D6*3 Allele - CISMeF





Preferred Label : CYP2D6*3 Allele;

NCIt synonyms : CYP2D6*3; CYP2D6, g.2549delA; Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*3 Allele; CYP2D6A; CYP2D6 3 Allele;

NCIt definition : Human CYP2D6*3 allele is located in the vicinity of 22q13.1 and is approximately 4 kb in length. This allele, a variant form of the CYP2D6 wild-type allele, encodes cytochrome P450 2D6*3 protein. The CYP2D6*3 allele exhibits a single nucleotide deletion (g.2549A del) that results in a frameshift during protein coding. This alteration abolishes the enzymatic activity of the cytochrome P450 2D6*3 protein.;

NCIt note : Ethnicity Association: Asian; Caucasian;

GenBank Accession Number : NM_000106;

PubMed : 2211621;

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20/05/2024


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