" /> CYP3A4*17 Allele - CISMeF





Preferred Label : CYP3A4*17 Allele;

NCIt synonyms : CYP3A4, g.15615T C; CYP3A4, F189S; CYP3A4*17; Cytochrome P450, Family 3, Subfamily A, Polypeptide 4*17 Allele; CYP3A4 17 Allele;

NCIt definition : Human CYP3A4*17 allele is located in the vicinity of 7q21.1 and is approximately 27 kb in length. This allele, a variant form of the CYP3A4 wild-type allele, encodes cytochrome P450 3A4*17 protein. The CYP3A4*17 allele exhibits a clinically-relevant SNP (g.15615T C) in exon 7 that results in a F189S coding change. This alteration in protein sequence severely decreases the enzymatic activity of the cytochrome P450 3A4*17 protein.;

NCIt note : Ethnicity Association: Asian;

GenBank Accession Number : NM_017460;

SNP ID : rs4987161;

PubMed : 11714865;

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28/04/2024


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