" /> CYP3A5*10 Allele - CISMeF





Preferred Label : CYP3A5*10 Allele;

NCIt synonyms : Cytochrome P450, Family 3, Subfamily A, Polypeptide 5*10 Allele; CYP3A5, g.6986A G; CYP3A5*10; CYP3A5 10 Allele;

NCIt definition : Human CYP3A5*10 allele is located in the vicinity of 7q21.1 and is approximately 32 kb in length. This allele, a variant form of the human CYP3A5 wild-type allele, encodes cytochrome P450 3A5*10 protein. This allele exhibits a clinically-relevant SNP (g.6986A G) in exon 10 that causes a splicing defect. The resulting alteration in protein sequence almost completely abolishes the enzymatic activity of the cytochrome P450 3A5*10 protein.;

NCIt note : Ethnicity Association: Caucasian;

GenBank Accession Number : NM_000777;

SNP ID : rs776746;

PubMed : 12398984;

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28/04/2024


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