" /> CYP2C9*18 Allele - CISMeF





Preferred Label : CYP2C9*18 Allele;

NCIt synonyms : CYP2C9, D397A; CYP2C9*18; Cytochrome P450, Family 2, Subfamily C, Polypeptide 9*18 Allele; CYP2C9, c.1190A C; CYP2C9 18 Allele;

NCIt definition : Human CYP2C9*18 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9 wild-type allele, encodes cytochrome P450 2C9*18 protein. The CYP2C9*18 allele exhibits a clinically-relevant SNP (c.1190A C) in exon 8 that results in a D397A coding change. This alteration in protein sequence decreases the in vivo enzymatic activity of the cytochrome P450 2C9*18 protein.;

NCIt note : Ethnicity Association: Asian;

GenBank Accession Number : NM_000771;

PubMed : 15371982;

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20/05/2024


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