" /> CYP2C9*12 Allele - CISMeF





Preferred Label : CYP2C9*12 Allele;

NCIt synonyms : CYP2C9*12; CYP2C9, P489S; CYP2C9, c.1465C T; Cytochrome P450, Family 2, Subfamily C, Polypeptide 9*12 Allele; CYP2C9 12 Allele;

NCIt definition : Human CYP2C9*12 allele is located within 10q24 and is approximately 33 kb in length. This allele, a variant form of the CYP2C9 wild-type allele, encodes cytochrome P450 2C9*12 protein. The CYP2C9*12 allele exhibits a clinically-relevant SNP (c.1465C T) in exon 9 that results in a P489S coding change. This alteration in protein sequence decreases the enzymatic activity of the cytochrome P450 2C9*12 protein.;

NCIt note : Ethnicity Association: None Established;

GenBank Accession Number : NM_000771;

SNP ID : rs9332239;

PubMed : 15284535;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
25/05/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.