NCIt definition : Human CYP2C9*8 allele is located within 10q24 and is approximately 33 kb in length.
This allele, a variant form of the CYP2C9 wild-type allele, encodes cytochrome P450
2C9*8 protein. The CYP2C9*8 allele exhibits a clinically-relevant SNP (c.449G A) in
exon 3 that results in a R150H coding change. This alteration in protein sequence
increases the enzymatic activity of the cytochrome P450 2C9*8 protein.;
NCIt note : Ethnicity Association: African American; Black African;