" /> CYP2C19*12 Allele - CISMeF





Preferred Label : CYP2C19*12 Allele;

NCIt synonyms : Cytochrome P450, Family 2, Subfamily C, Polypeptide 19*12 Allele; CYP2C19, c.1473A C; CYP2C19*12; CYP2C19, X491C; CYP2C19 12 Allele;

NCIt definition : Human CYP2C19*12 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19 wild-type allele, encodes cytochrome P450 2C19*12 protein. The CYP2C19*12 allele exhibits a clinically-relevant SNP (c.1473A C) in exon 9 that results in a X491C coding change. This alteration yields an unstable cytochrome P450 2C19*12 protein that is predicted to have an additional 26 amino acids.;

NCIt note : Ethnicity Association: African American;

GenBank Accession Number : NM_000769;

PubMed : 12464799;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
10/07/2025


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.