" /> CYP2C19*10 Allele - CISMeF





Preferred Label : CYP2C19*10 Allele;

NCIt synonyms : CYP2C19, P227L; CYP2C19*10; CYP2C19, c.680C T; Cytochrome P450, Family 2, Subfamily C, Polypeptide 19*10 Allele; CYP2C19 10 Allele;

NCIt definition : Human CYP2C19*10 allele is located within 10q24.1-q24.3 and is approximately 90 kb in length. This allele, a variant form of the CYP2C19 wild-type allele, encodes cytochrome P450 2C19*10 protein. The CYP2C19*10 allele exhibits a clinically-relevant SNP (c.680C T) in exon 5 that results in a P227L coding change. This alteration in protein sequence severely decreases the enzymatic activity of the cytochrome P450 2C19*10 protein.;

NCIt note : Ethnicity Association: African American;

GenBank Accession Number : NM_000769;

SNP ID : rs6413438;

PubMed : 12464799;

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31/05/2024


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