" /> CYP2D6*2N Allele - CISMeF





Preferred Label : CYP2D6*2N Allele;

NCIt synonyms : Cytochrome P450, Family 2, Subfamily D, Polypeptide 6*2N Allele; CYP2D6*2XN; CYP2D6 2N Allele;

NCIt definition : Human CYP2D6*2N allele, a variant form of the CYP2D6 wild-type allele, is approximately 4 kb in length and encodes cytochrome P450 2D6 protein. Amplification of the CYP2D6 gene (up to 12 copies) produces the CYP2D6*2N allele. The enzymatic activity of the protein encoded by this allele is not significantly different from the protein product of the wild-type allele. However, individuals who carry this allele exhibit an ultra-rapid metabolizer phenotype.;

NCIt note : Ethnicity Association: Asian; African American; Black African; Caucasian; Middle Eastern;

GenBank Accession Number : NM_000106;

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17/10/2025


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