Phenacetin - CISMeF

Preferred Label : Phenacetin;

NCIt synonyms : Acetophenetin; p-Acetophenetidide; para Acetylphenetidin; N-(4-ethoxyphenol)acetamide; 1-Acetamido-4-ethoxybenzene; 4-Ethoxy Acetanilide;

NCIt definition : A synthetic, white crystalline solid that is slightly soluble in water and benzene, soluble in acetone and very soluble in pyrimidine. It is used in research as the preferred marker for detecting CYP1A2-based inhibition potential in vitro. Human ingestion of phenacetin can result in a bluish discoloration of the skin due to a lack of oxygen in the blood (cyanosis), dizziness and respiratory depression. It is reasonably anticipated to be a human carcinogen. (NCI05);

UNII : ER0CTH01H9;

InChIKey : CPJSUEIXXCENMM-UHFFFAOYSA-N;

CAS number : 62-44-2;

Chemical formula : C10H13NO2;

NSC code : 7651;

ChEBI ID : CHEBI:8050;

Codes from synonyms : 00230;

Details

Origin ID

C44432;

UMLS CUI

C0031364;

Semantic type(s)
- Hazardous or Poisonous Substance [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Phenacetin [ICD-11 Extension code]
- Phenacetin [LOINC component]
- Phenacetin (substance) [SNOMED CT concept]
- phenacetin [ATC Code]
- phenacetin [Substance BNPC]
- phenacetin [SNOMED Notion]
- phenacetin [MeSH concept]
- phenacetin [MeSH Descriptor]
Validated automatic mappings to BTNT
- phenacetin [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 1A2 [NCIt concept]
- Cytochrome P450 2D6 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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