Dinitrofluorobenzene

Preferred Label : Dinitrofluorobenzene;

NCIt synonyms : 2,4-nitrofluorobenzene; 2,4-dinitrobenzene fluoride; Sanger's Reagent; DNFB;

NCIt related terms : 1-Fluoro-2,4-dinitrobenzene;

NCIt definition : An aromatic hydrocarbon composed of a benzene ring linked to two nitro groups and one fluoride group that is used for N-terminal amino acid sequencing by the Sanger method. In vitro, dinitrofluorobenzene (DNFB) reacts with the amine group in amino acids to produce dinitrophenyl (DNP)-amino acids. Then the sample is subjected to acid hydrolysis. Under these conditions, the peptide bonds are broken but the DNP-amino acid bonds remain intact. The DNP-amino acids can be recovered and their identities can be determined through the use of various chromatography techniques. This reagent can also be used to distinguish the reduced and oxidized forms of glutathione and cysteine.;

UNII : D241E059U6;

CAS number : 70-34-8;

Chemical formula : C6H3FN2O4;

NSC code : 33519;

ChEBI ID : CHEBI:53049;

Codes from synonyms : NSC0033519;

Details

Origin ID

C440;

UMLS CUI

C0012463;

Automatic exact mappings (from CISMeF team)
- 1,4-dithiothreitol [Substance BNPC]
- 2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-disulfide [MeSH Supplementary Concept]
- 2,4-bis(4-methoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulphide [Substance BNPC]
- 2,6-Dichloroindophenol [MeSH Descriptor]
- 2-hydroxy-5-nitrobenzyl bromide [MeSH Descriptor]
- 2-hydroxy-5-nitrobenzyl bromide [Substance BNPC]
- 3,3'-dithiobis[6-nitrobenzoic] acid [Substance BNPC]
- 4-(dimethylamino)benzaldehyde [Substance BNPC]
- Fouchet stain (substance) [SNOMED CT concept]
- diazobenzenesulfonic acid [MeSH Supplementary Concept]
- dithionitrobenzoic acid [MeSH Descriptor]
- dithiothreitol [MeSH Descriptor]
- fenton's reagent [MeSH concept]
- fenton's reagent [MeSH Supplementary Concept]
- marfey's reagent [MeSH concept]
- marfey's reagent [MeSH Supplementary Concept]
- schiff's reagent [MeSH concept]
- schiff's reagent [MeSH Supplementary Concept]
- trinder's reagent [MeSH concept]
- trinder's reagent [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- dinitrofluorobenzene [Substance BNPC]
- dinitrofluorobenzene [MeSH Descriptor]
- dinitrofluorobenzene [MeSH concept]
False automatic mappings
- tetramethylphenylenediamine [MeSH Descriptor]
Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- dinitrofluorobenzene [Substance BNPC]
- dinitrofluorobenzene [MeSH concept]
- dinitrofluorobenzene [MeSH Descriptor]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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