dithiothreitol

Preferred Label : dithiothreitol;

MeSH definition : A reagent commonly used in biochemical studies as a protective agent to prevent the oxidation of SH (thiol) groups and for reducing disulphides to dithiols.;

MeSH synonym : clelands reagent; reagent, cleland's; reagent, cleland; cleland reagent; cleland's reagent;

MeSH hyponym : sputolysin;

MeSH CAS label : 2,3-Butanediol, 1,4-dimercapto-, (R*,R*)-;

MeSH Related Number : 3483-12-3 (Dithiothreitol);

Registry Number MeSH : 3483-12-3;

Wikipedia link : https://en.wikipedia.org/wiki/Dithiothreitol;

Codes EINECS : 222-468-7;

Is substance : O;

UNII : T8ID5YZU6Y;

InChIKey : VHJLVAABSRFDPM-IMJSIDKUSA-N;

Details

Origin ID

D004229;

UMLS CUI

C0012789;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- 2,4-bis(4-methoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulphide [Substance BNPC]
- 2-hydroxy-5-nitrobenzyl bromide [Substance BNPC]
- 3,3'-dithiobis[6-nitrobenzoic] acid [Substance BNPC]
- 4-(dimethylamino)benzaldehyde [Substance BNPC]
- Dinitrofluorobenzene [NCIt concept]
- Fouchet stain (substance) [SNOMED CT concept]
CISMeF manual mappings
- 1,4-dithiothreitol [Substance BNPC]
Currated CISMeF NLP mapping
- Dithiothreitol [NCIt concept]
Record concept(s)
- dithiothreitol [MeSH concept]
- sputolysin [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1-S-(3H)carboxymethyl-dithiothreitol [MeSH Supplementary Concept]
- S-nitrosodithiothreitol [MeSH Supplementary Concept]
- dithiothreitol tetraacetate [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 1,4-dithiothreitol [Substance BNPC]
- Dithiothreitol [NCIt concept]

Keyword's position in hierarchy(ies) :

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