Preferred Label : Deferoxamine;
NCIt synonyms : 1-Amino-6,17-dihydroxy-7,10,18,21-tetraoxo-27-(n-acetylhydroxylamino)-6,11,17,22-tetraazaheptaeicosane; N-[5-[3-[(5-Aminopentyl)hydroxycarbamoyl]propionamido]pentyl]-3-[[5-(N-hydroxyacetamido)pentyl]carbamoyl]propionohydroxamic
Acid; DFO-B; Desferoxamine B; Desferrioxamine B;
NCIt related terms : Desferrioxamine; N'-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxybutanediamide;
NCIt definition : An iron-chelating agent that binds free iron in a stable complex, preventing it from
engaging in chemical reactions. Deferoxamine chelates iron from intra-lysosomal ferritin
and siderin forming ferrioxamine, a water-soluble chelate excreted by the kidneys
and in the feces via the bile. This agent does not readily bind iron from transferrin,
hemoglobin, myoglobin or cytochrome. (NCI04);
Alternative definition : NCI-GLOSS: An iron-chelating agent that removes iron from tumors by inhibiting DNA
synthesis and causing cancer cell death. It is used in conjunction with other anticancer
agents in pediatric neuroblastoma therapy.;
UNII : J06Y7MXW4D;
InChIKey : UBQYURCVBFRUQT-UHFFFAOYSA-N;
CAS number : 70-51-9; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 70-51-9
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G-SRS /a ;
Chemical formula : C25H48N6O8;
NSC code : 527604;
ChEBI ID : CHEBI:4356;
Codes from synonyms : NSC0527604; CDR0000045388; 09403; 149;
Origin ID : C416;
UMLS CUI : C0011145;
Automatic exact mappings (from CISMeF team)
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
- has_salt_form
- has_target
- is_free_acid_or_base_form_of
