Deferoxamine Mesylate

Preferred Label : Deferoxamine Mesylate;

NCIt synonyms : Deferoxamine B; Desferrioxamine Mesylate; Deferoxamine Methanesulfonate; Deferrioxamine B; DFM;

NCIt related terms : Desferal;

NCIt definition : The mesylate salt of an iron-chelating agent that binds free iron in a stable complex, preventing it from engaging in chemical reactions. Deferoxamine chelates iron from intra-lysosomal ferritin and ferrioxamine, a water-soluble complex excreted by the kidneys and in the feces via the bile. This agent does not readily chelate iron bound to transferrin, hemoglobin, myoglobin or cytochrome.;

UNII : V9TKO7EO6K;

InChIKey : IDDIJAWJANBQLJ-UHFFFAOYSA-N;

CAS number : 138-14-7;

Drug name : Desferal;

Chemical formula : C25H48N6O8.CH4O3S;

NSC code : 644468;

ChEBI ID : CHEBI:31460;

Codes from synonyms : NSC0644468; NSC0527604;

Details

Origin ID

C417;

UMLS CUI

C0011148;

Automatic exact mappings (from CISMeF team)
- deferoxamine [MeSH Descriptor]
False automatic mappings
- fibromuscular dysplasia [MeSH Descriptor]
Semantic type(s)
- Indicator, Reagent, or Diagnostic Aid [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Deferoxamine mesilate (substance) [SNOMED CT concept]
- Deferoxamine mesylate (product) [Inactive SNOMED CT concept]
- deferoxamine mesilate [Substance BNPC]
- deferoxamine mesylate [International Nonproprietary Name]
- deferoxamine mesylate [SNOMED Notion]
- desferrioxamine B mesylate [MeSH concept]
Validated automatic mappings to NTBT
- deferoxamine [MeSH Descriptor]
- deferoxamine [MeSH concept]
- deferoxamine [Substance BNPC]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_free_acid_or_base_form
- Deferoxamine [NCIt concept]
has_target
- Iron [NCIt concept]
is_salt_form_of
- Deferoxamine [NCIt concept]

Keyword's position in hierarchy(ies) :

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