Glutamate-Cysteine Ligase Regulatory Subunit

Preferred Label : Glutamate-Cysteine Ligase Regulatory Subunit;

NCIt synonyms : Glutamate-Cysteine Ligase; Glutamate-Cysteine Ligase Modifier Subunit; GSC Light Chain; GLCLR; Gamma-Glutamylcysteine Synthetase; Gamma-ECS Regulatory Subunit; Gamma-Glutamylcysteine Synthetase 30.8kD Protein; Glutamate-Cysteine Ligase Regulatory Protein; Gamma-ECS; GCLM; Glutamate--Cysteine Ligase Regulatory Subunit; Gamma-Glutamylcysteine Synthetase Regulatory Protein; GCS Light Chain; Glutamate-Cysteine Ligase, Regulatory Subunit; Glutamate--Cysteine Ligase Modifier Subunit;

NCIt definition : Glutamate-cysteine ligase regulatory subunit (274 aa, 31 kDa) is encoded by the human GCLM gene. This protein is involved in glutathione biosynthesis.;

NCIt note : Protein_Plays_Role_In_Biological_Process: Glutathione Biosynthesis;

Details

Origin ID

C38606;

UMLS CUI

C1522380;

False automatic mappings
- Glutamate-cysteine ligase (substance) [SNOMED CT concept]
- glutamate-cysteine ligase [SNOMED Notion]
OMIM relation
- Glutamate-cysteine ligase, modifier subunit [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- GCLM protein, human [MeSH concept]
- GCLM protein, human [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- GCLM protein, human [MeSH Supplementary Concept]
- GCLM protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- GCLM Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_chemical_classification
- Protein Complex Subunit [NCIt concept]
gene_product_is_element_in_pathway
- Alanine, Aspartate and Glutamate Metabolism Pathway [NCIt concept]
- Glutathione Metabolism Pathway [NCIt concept]
gene_product_is_physical_part_of
- Gamma-Glutamylcysteine Synthetase [NCIt concept]
gene_product_plays_role_in_biological_process
- Detoxification [NCIt concept]
- Peptide Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients