Nuclear Factor 1 X-Type

Preferred Label : Nuclear Factor 1 X-Type;

NCIt synonyms : CTF; CCAAT-Binding Transcription Factor; NFIX; NF-I/X; Nuclear Factor I/X; TGGCA-Binding Protein; NFI-X; CCAAT-Box-Binding Transcription Factor; NF-IX Protein; NF1-X;

NCIt definition : Nuclear factor 1 X-type (502 aa, 55 kDa) is encoded by the human NFIX gene. This protein is involved in both DNA replication and transcription.;

NCIt note : Nuclear factor 1 X-type recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters. (UniProt);

Details

Origin ID

C38406;

UMLS CUI

C1522145;

Currated CISMeF NLP mapping
- nuclear factor I-X [MeSH concept]
OMIM relation
- Nuclear factor I/x [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- NFIX protein, human [MeSH concept]
- NFIX protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- NFIX Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- DNA Replication [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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