Nuclear Factor 1 C-Type

Preferred Label : Nuclear Factor 1 C-Type;

NCIt synonyms : NFIC; CTF; CCAAT-Box-Binding Transcription Factor; Nuclear Factor 1/C; TGGCA-Binding Protein; CCAAT-Binding Transcription Factor; NFI-C; CCAAT-Box Binding Transcription Factor; NF1-C; Nuclear Factor I/C; NF-IC Protein; NF-I/C;

NCIt definition : Nuclear factor 1 C-type (508 aa, 56 kDa) is encoded by the human NFIC gene. This protein plays a role in the modulation of gene transcription and the regulation of DNA replication.;

NCIt note : Nuclear factor 1 C-type recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters. (UniProt);

Details

Origin ID

C38404;

UMLS CUI

C1522146;

Currated CISMeF NLP mapping
- nuclear factor I-C [MeSH concept]
OMIM relation
- Nuclear factor I/c [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- NFIC protein, human [MeSH concept]
- NFIC protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- NFIC Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- DNA Replication [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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