Nuclear Factor 1 B-Type

Preferred Label : Nuclear Factor 1 B-Type;

NCIt synonyms : NFI-B; Nuclear Factor I/B; NF-I/B; NFIB; TGGCA-Binding Protein; NF-IB Protein; NF1-B; Nuclear Factor 1/B; NFIB2; NFI-RED; NF-IB; CCAAT-Box Binding Transcription Factor; CTF; NFIB3;

NCIt definition : Nuclear factor 1 B-type (420 aa, 47 kDa) is encoded by the human NFIB gene. This protein is involved in the mediation of both DNA replication and transcriptional regulation.;

NCIt note : Nuclear factor 1 B-type recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters. (UniProt);

Details

Origin ID

C38402;

UMLS CUI

C1431185;

Currated CISMeF NLP mapping
- nuclear factor I-B [MeSH concept]
OMIM relation
- Nuclear factor I/b [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- NFIB protein, human [MeSH concept]
- NFIB protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- NFIB Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- DNA Replication [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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