Nuclear Factor 1 A-Type

Preferred Label : Nuclear Factor 1 A-Type;

NCIt synonyms : NFIA; Nuclear Factor 1/A; NF1-A; TGGCA-Binding Protein; NF-IA Protein; NFI-L; NF-IA; CCAAT-Box Binding Transcription Factor; Nuclear Factor I/A; NF-I/A; NFI-A; CTF;

NCIt definition : Nuclear factor 1 A-type (509 aa, 56 kDa) is encoded by the human NFIA gene. This protein plays a role in the regulation of both gene replication and transcription.;

NCIt note : Nuclear factor 1 A-type recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters. (UniProt);

Details

Origin ID

C38400;

UMLS CUI

C1455428;

Currated CISMeF NLP mapping
- nuclear factor I-A [MeSH concept]
OMIM relation
- Nuclear factor I/a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- NFIA protein, human [MeSH concept]
- NFIA protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- NFIA Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- DNA Replication [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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