t(5;14)(q31.1;q32.3)

Preferred Label : t(5;14)(q31.1;q32.3);

NCIt synonyms : t 5 14 q31 q32; t(5;14)(q31;q32);

NCIt definition : A chromosomal translocation involving breakpoints within the q31.1 band on the long arm of chromosome 5 and the q32.3 band on the long arm of chromosome 14. This rearrangement is associated with aberrant expression of the IL3 gene and B-cell acute lymphoblastic leukemia (ALL) with hypereosinophilia.;

Details

Origin ID

C36358;

UMLS CUI

C1515775;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
cytogenetic_abnormality_involves_chromosome
- Human Chromosome 14 [NCIt concept]
- Human Chromosome 5 [NCIt concept]
is_abnormality_of_gene
- IGH/IL3 Fusion Gene [NCIt concept]
is_cytogenetic_abnormality_of_disease
- B Acute Lymphoblastic Leukemia with t(5;14)(q31.1;q32.3); IL3-IGH [NCIt concept]
- B Lymphoblastic Leukemia/Lymphoma with t(5;14)(q31.1;q32.3); IL3-IGH [NCIt concept]
molecular_abnormality_involves_gene
- IGH/IL3 Fusion Gene [NCIt concept]
- IL3 Gene [NCIt concept]
- Immunoglobulin Heavy Component Gene [NCIt concept]
- Immunoglobulin Heavy Locus [NCIt concept]

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