" /> IGH/IL3 Fusion Gene - CISMeF





Preferred Label : IGH/IL3 Fusion Gene;

NCIt synonyms : IGH-IL3; IGH::IL3 Fusion Gene; IGH-IL3 Fusion Gene;

NCIt related terms : IGH::IL3 Fusion;

NCIt definition : A fusion gene that results from a chromosomal translocation, t(5;14)(q31;q32), which results in the juxtaposition of a strong transcriptional enhancer from the immunoglobulin heavy chain (IGH) gene locus with the promoter region of the IL3 gene. This rearrangement is associated with B-cell acute lymphoblastic leukemia with hypereosinophilia.;

NCIt note : This fusion results in aberrant expression of the interleukin-3 protein.;

NCI Metathesaurus CUI : CL1799603;

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31/05/2025


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